Exploration of Insect Growth Regulators Targeting Noppera-bo, an Enzyme Involved in Ecdysteroid Biosynthesis
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چکیده
منابع مشابه
Effect of two insect growth regulators on the ecdysteroid contents in eggs of the mealworm
RH-0345 (halofenozide), a bisacylhydrazine derivative, is a nonsteroidal ecdysteroid agonist that mimics the action of the moulting hormones, while KK-42, an imidazole compound, is a potent inhibitor of ecdysteroid biosynthesis. Previous results suggested that the observed reduction of ecdysteroid titre, leading to a reduction of reproductive capacity in the mealworm Tenebrio molitor, is due to...
متن کاملA Halloween gene noppera-bo encodes a glutathione S-transferase essential for ecdysteroid biosynthesis via regulating the behaviour of cholesterol in Drosophila
In insects, the precise timing of moulting and metamorphosis is strictly guided by ecdysteroids that are synthesised from dietary cholesterol in the prothoracic gland (PG). In the past decade, several ecdysteroidogenic enzymes, some of which are encoded by the Halloween genes, have been identified and characterised. Here, we report a novel Halloween gene, noppera-bo (nobo), that encodes a membe...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2018
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.17-00211-3